NIGMS National and Regional Resources (R24 - Clinical Trial Not Allowed) | PAR 22 065

Opportunity Information: Apply for PAR 22 065

The NIGMS National and Regional Resources program (R24, Clinical Trial Not Allowed) is a National Institutes of Health funding opportunity designed to keep high-value, shared biomedical research resources running at a national or multi-state regional scale. The main goal is to support established facilities or service-oriented resource centers that give a broad community of researchers access to advanced capabilities they could not easily maintain on their own, such as specialized equipment, cutting-edge technologies, research tools, software platforms tied to a service operation, and the expert staff needed to operate them. The emphasis is on enabling wide access and strong utilization across many institutions, rather than funding traditional investigator-driven research projects.

A key feature of this opportunity is that the supported resource must function as a true service resource: it should provide research capabilities and expertise to a large number of investigators and be available to any qualified user, rather than being restricted to a single lab, department, or narrow set of projects. NIGMS is looking for resources that already exist and have demonstrated value, stability, and demand. New resources are only appropriate if they are formed by consolidating multiple local or regional operations into a single, more efficient resource that can deliver clear economies of scale and expand access to more users. In other words, the program is meant to strengthen and broaden access to proven capabilities, not to incubate early-stage concepts.

The FOA is also clear about what it does not want to support. Major new research and development is out of scope; this mechanism is intended for operations, access, and sustained availability rather than building an R&D program to invent new technologies. Clinical trials are not allowed under this announcement. In addition, stand-alone data resources and databases are not eligible, meaning a proposal that is essentially just a data repository (without an integrated, service-based resource component) would not fit. Another important boundary is duplication: applicants need to show that the proposed resource does not duplicate or replace capabilities that are already supported by other NIH Institutes and Centers or that should be provided by the host institution as routine infrastructure. The resource also must align with NIGMS program areas, since NIGMS will only support resources whose technical capabilities fall within its scientific mission.

From an operational standpoint, NIGMS expects awardees to keep the resource at current best practices, which generally implies routine modernization, maintenance, and incremental upgrades needed to remain state of the art. The resource should also actively promote awareness of its capabilities to the broader biomedical research community through outreach, and it should provide training and user support so that investigators from different institutions can effectively access and use the technologies or services. The overall picture is a mature, highly utilized shared resource with strong governance and a clear plan to deliver reliable service at scale.

Eligibility is broad across U.S.-based organizations, spanning government entities (state, county, city/township, special districts), public and private institutions of higher education, independent school districts, federally recognized Native American tribal governments, tribal organizations, public housing authorities/Indian housing authorities, nonprofits (with or without 501(c)(3) status), for-profit organizations (other than small businesses), and small businesses. The announcement also highlights inclusion of various institution types such as HBCUs, Hispanic-serving institutions, AANAPISI institutions, Tribal Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, and regional organizations. At the same time, foreign participation is tightly restricted: non-U.S. entities and foreign institutions are not eligible to apply, non-domestic components of U.S. organizations are not eligible, and foreign components (as NIH defines them) are not allowed.

Administratively, this is a discretionary grant opportunity from NIH, listed under CFDA 93.859, with the Funding Opportunity Number PAR-22-065. The original closing date shown is June 14, 2024. The award ceiling and expected number of awards are not specified in the provided listing. Finally, an important constraint unique to this FOA is that it is limited to resources that were developed through previous NIGMS funding, meaning applicants generally need to demonstrate an NIGMS-supported origin and a track record showing that the resource is already functioning and ready for continued, scaled service to a broad user base.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIGMS National and Regional Resources (R24 - Clinical Trial Not Allowed)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.859.
• This funding opportunity was created on 2021-11-29.
• Applicants must submit their applications by 2024-06-14. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

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