Opportunity Information: Apply for PAR 21 351
The NIA Career Transition Award (K22 Independent Clinical Trial Not Allowed), funding opportunity number PAR-21-351, is a discretionary NIH grant designed to help mentored researchers move into independent, tenure-track faculty roles while continuing work that aligns with the mission of the National Institute on Aging (NIA). The central goal is to bridge a critical career gap between postdoctoral or other mentored stages and an independent academic appointment by providing three years of support that protects the recipient's time for research. In practice, that support is delivered through a combination of salary support and research funding, giving awardees the space to establish an independent research direction, publish, generate preliminary data, and compete effectively for larger independent research awards later.
This opportunity is specifically aimed at investigators who expect to begin a tenure-track faculty position within about one year of receiving the award, making it a structured transition mechanism rather than a long-term mentored training grant. As indicated by the title, independent clinical trials are not allowed under this announcement, so applicants need to propose research and career development activities that do not include running an independent clinical trial as the primary study. The award falls under the NIH health funding activity category and is associated with CFDA number 93.866, reflecting NIA's broader research portfolio in aging.
Eligibility is broad at the organizational level and includes many types of U.S.-based entities such as state, county, city or township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations that are not federally recognized; public housing authorities and Indian housing authorities; nonprofits with or without 501(c)(3) status (when not an institution of higher education); for-profit organizations that are not small businesses; small businesses; and other eligible applicants as defined by NIH policy. The announcement also explicitly highlights additional eligible organizations, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, certain eligible federal agencies, regional organizations, and U.S. territories or possessions. These inclusions signal an intent to support a wide range of institutional contexts and to encourage participation across diverse research environments.
At the same time, the opportunity clearly restricts non-U.S. involvement. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply, non-domestic components of U.S. organizations are not eligible, and foreign components (as defined by the NIH Grants Policy Statement) are not allowed. In other words, the applicant organization and the supported project activities must remain within allowable domestic boundaries under NIH rules.
Administrative details in the source information show the sponsoring agency as the National Institutes of Health, the funding instrument as a grant, and the original closing date listed as 2024-02-24. The opportunity record was created on 2021-09-28. The provided source excerpt does not specify an award ceiling or the expected number of awards, so applicants typically need to consult the full NIH announcement for budget limits, allowable costs, and any institute-specific guidance on salary and research support levels.Apply for PAR 21 351
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIA Career Transition Award (K22 Independent Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866.
- This funding opportunity was created on 2021-09-28.
- Applicants must submit their applications by 2024-02-24. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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FAQs: NIA Career Transition Award (K22 Independent Clinical Trial Not Allowed) - PAR-21-351
What is the NIA Career Transition Award (K22) under PAR-21-351?
The NIA Career Transition Award (K22 Independent Clinical Trial Not Allowed), funding opportunity number PAR-21-351, is a discretionary NIH grant from the National Institute on Aging (NIA). It is designed to help mentored researchers transition into independent, tenure-track faculty roles while continuing research aligned with NIA's mission in aging.
What is the main purpose of this K22 opportunity?
The central purpose is to bridge the career gap between postdoctoral (or other mentored) stages and an independent academic appointment. It does this by providing structured support intended to protect the recipient's time for research while they establish independence.
How long does the K22 provide support?
The opportunity provides three years of support.
What types of support does the award provide?
Support is described as a combination of salary support and research funding. The intent is to give awardees space to develop an independent research direction, publish, generate preliminary data, and become competitive for larger independent research awards later.
Who is this award intended for?
It is aimed at mentored investigators (for example, postdoctoral or other mentored-stage researchers) who are preparing to move into independent, tenure-track faculty positions.
How soon is the applicant expected to start a tenure-track faculty position?
This opportunity is specifically aimed at investigators who expect to begin a tenure-track faculty position within about one year of receiving the award, indicating it is meant as a structured transition mechanism rather than a long-term training grant.
Are independent clinical trials allowed under this announcement?
No. As indicated by the title, independent clinical trials are not allowed under this funding opportunity. Applicants need to propose research and career development activities that do not include running an independent clinical trial as the primary study.
What does "Independent Clinical Trial Not Allowed" mean for applicants?
Based on the information provided, it means the proposed work should not involve the applicant running an independent clinical trial as the primary study. Applicants should shape their plans around research and career development activities that fit within this limitation.
Which agency sponsors this funding opportunity?
The sponsoring agency is the National Institutes of Health (NIH), and it is associated with the National Institute on Aging (NIA).
What is the funding instrument type?
The funding instrument is a grant.
What is the funding opportunity number?
The funding opportunity number is PAR-21-351.
What is the related CFDA number?
The opportunity is associated with CFDA number 93.866, reflecting NIA's broader research portfolio in aging.
What types of organizations are eligible to apply (in general)?
Eligibility at the organizational level includes a wide range of U.S.-based entities, such as state, county, city or township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; tribal governments and tribal organizations; public housing authorities; nonprofits with or without 501(c)(3) status (when not an institution of higher education); for-profit organizations that are not small businesses; small businesses; and other eligible applicants as defined by NIH policy.
Are higher education institutions eligible?
Yes. Public and state-controlled institutions of higher education and private institutions of higher education are included among eligible organization types.
Are nonprofits eligible?
Yes. Nonprofits with or without 501(c)(3) status (when not an institution of higher education) are included among eligible organization types.
Are for-profit organizations eligible?
Yes. For-profit organizations that are not small businesses, as well as small businesses, are included among the listed eligible organization types.
Are tribal governments and tribal organizations eligible?
Yes. Federally recognized Native American tribal governments and Native American tribal organizations that are not federally recognized are listed as eligible.
Are U.S. territories or possessions eligible?
Yes. The announcement explicitly highlights U.S. territories or possessions among additional eligible organizations.
Does the announcement encourage applications from specific types of institutions?
Yes. The announcement explicitly highlights additional eligible organizations, including Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISIs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); as well as faith-based or community-based organizations, certain eligible federal agencies, regional organizations, and U.S. territories or possessions.
Are foreign institutions or non-U.S. entities eligible to apply?
No. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply.
Can a U.S. organization include a non-U.S. component in the application?
No. Non-domestic components of U.S. organizations are not eligible.
Are foreign components allowed in any form?
No. Foreign components (as defined by the NIH Grants Policy Statement) are not allowed under this opportunity.
What is the implication of the domestic-only restriction?
Based on the provided information, the applicant organization must be eligible as a U.S.-based entity, and the supported project activities must remain within allowable domestic boundaries under NIH rules.
What is the original closing date listed for this opportunity?
The original closing date listed in the provided information is 2024-02-24.
When was the opportunity record created?
The opportunity record was created on 2021-09-28.
Does the provided information specify an award ceiling or number of awards?
No. The excerpt does not specify an award ceiling or the expected number of awards.
Where should applicants look for budget limits and allowable costs?
Because the excerpt does not include budget limits or award counts, applicants typically need to consult the full NIH announcement for budget limits, allowable costs, and any institute-specific guidance on salary and research support levels.
What kinds of outcomes is this award intended to support during the transition period?
The award is intended to help recipients establish an independent research direction, publish, generate preliminary data, and compete effectively for larger independent research awards later.
Is this K22 described as a long-term mentored training grant?
No. It is described as a structured transition mechanism meant to support the move into an independent, tenure-track role rather than serving as a long-term mentored training grant.
What research area should the proposed work align with?
The proposed research should align with the mission of the National Institute on Aging (NIA), within NIH's broader health research funding context.
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