Opportunity Information: Apply for ARPA H MAI 24 01
The Master Announcement Instructions (MAI), ARPA-H MAI 24 01, is a standing set of instructions from the Advanced Research Projects Agency for Health (ARPA-H) meant to standardize how applicants respond to future ARPA-H "Module Announcements." It is not, by itself, a funding solicitation you apply to directly. Instead, it functions as a common rulebook that module-specific solicitations will reference, so applicants do not have to relearn a different format and submission process each time.
A central goal of the MAI is to introduce tiered proposal submission requirements, meaning the application burden is scaled to the size and complexity of the effort being proposed. In practical terms, smaller or more limited-scope efforts are intended to require less writing and fewer supporting details than larger, higher-dollar efforts. Another stated objective is to reduce the upfront cost and pricing workload, lowering barriers for non-traditional performers that may not have the infrastructure or experience to assemble extensive cost documentation early in the process. The expectation is that module announcements that point back to the MAI will explain exactly how the tiers apply for that specific opportunity and what materials are required at each tier.
Eligibility is framed broadly at the module level: any responsible source capable of meeting the government need may submit a proposal in response to a module announcement. The notice specifically calls out universities, nonprofit organizations, small businesses, and other-than-small businesses as eligible and encouraged participants. The MAI also includes updated language related to Federally Funded Research and Development Centers (FFRDCs) and government entities, reflecting how those organizations may be addressed within the overall submission and eligibility framework when a module announcement incorporates the MAI requirements.
Amendment 1, dated June 25, 2024, updates the MAI in several administrative and procedural ways. It makes administrative edits across multiple sections (including 1.1, 1.2, 2.1.2, 3.1, 3.2, and 5.2.6), replaces Section 2.1.1 with new language dealing specifically with FFRDCs and government entities, and updates the evaluation criteria by revising Evaluation Criteria #2 in Section 4.2 to remove a reference to government entities (with the note that this particular removal is not highlighted). It also changes terminology throughout the document from "Abstract" to "Solution Summaries" without changing the underlying intent, updates proposal submission instructions in Sections 3.2, and removes the Stage 2 Notification Letter from Section 5.1. The amendment notes that changes are highlighted in yellow, except for the one evaluation-criteria edit described above.
The opportunity listing also clarifies a naming issue: the title has been revised to reduce confusion, because it should have been labeled "Master Announcement Instruction (MAI)" rather than "ARPA-H BDF Tool Box." Administrative details in the listing describe the instrument type as a cooperative agreement under a discretionary program, with activity categories spanning health and science and technology research and development, and the CFDA/Assistance Listing number shown as 93.384. The listing includes an original closing date of October 20, 2024, but the key practical point remains that applicants should not submit proposals to the MAI itself; proposals are submitted only in response to a specific module announcement that incorporates the MAI instructions and provides the module-specific requirements, scope, and tier structure.Apply for ARPA H MAI 24 01
- The Advanced Research Projects Agency for Health in the health, science and technology and other research and development sector is offering a public funding opportunity titled "Master Announcement Instructions (MAI)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.384.
- This funding opportunity was created on 2023-10-20.
- Applicants must submit their applications by 2024-10-20. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Others.
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Frequently Asked Questions (FAQs)
1) What is ARPA-H MAI 24 01?
ARPA-H MAI 24 01 is the Master Announcement Instructions (MAI) issued by the Advanced Research Projects Agency for Health (ARPA-H). It is a standing set of instructions designed to standardize how applicants respond to future ARPA-H "Module Announcements."
2) Is the MAI itself a funding opportunity I can apply to?
No. The MAI is not, by itself, a funding solicitation you apply to directly. It functions as a common rulebook that future module-specific solicitations will reference.
3) If I cannot apply to the MAI directly, what do I apply to?
You submit proposals only in response to a specific ARPA-H Module Announcement that incorporates (references) the MAI and provides the module-specific scope, requirements, and tier structure.
4) Why did ARPA-H create a Master Announcement Instructions document?
The MAI is intended to reduce repeated effort for applicants by providing standardized formatting and submission instructions that can be reused across multiple ARPA-H Module Announcements, rather than requiring applicants to learn a new process every time.
5) What are "Module Announcements" and how do they relate to the MAI?
Module Announcements are the module-specific solicitations that describe the particular opportunity. When a Module Announcement points back to the MAI, the MAI supplies the common submission instructions while the Module Announcement supplies the details that are specific to that opportunity.
6) What is meant by "tiered proposal submission requirements"?
The MAI introduces tiered submission requirements where the application burden is scaled to the size and complexity of the proposed effort. Smaller or more limited-scope efforts are intended to require less writing and fewer supporting details than larger, higher-dollar efforts.
7) Where do the details about the tiers come from?
The MAI establishes the concept of tiers, but each Module Announcement that incorporates the MAI is expected to explain exactly how tiers apply for that particular opportunity and what materials are required at each tier.
8) How does the MAI aim to reduce applicant burden?
One stated objective is to reduce the upfront cost and pricing workload, lowering barriers for non-traditional performers that may not have the infrastructure or experience to assemble extensive cost documentation early in the process.
9) Who is eligible to submit under opportunities that use the MAI?
Eligibility is framed broadly at the module level: any responsible source capable of meeting the government need may submit a proposal in response to a Module Announcement.
10) What types of organizations are specifically encouraged to participate?
The notice specifically calls out universities, nonprofit organizations, small businesses, and other-than-small businesses as eligible and encouraged participants.
11) How does the MAI address FFRDCs and government entities?
The MAI includes updated language related to Federally Funded Research and Development Centers (FFRDCs) and government entities, reflecting how those organizations may be addressed within the overall submission and eligibility framework when a Module Announcement incorporates the MAI requirements.
12) What is Amendment 1 and when was it issued?
Amendment 1 is an update to the MAI dated June 25, 2024. It makes administrative and procedural updates and revises certain sections and evaluation-related language.
13) Which sections were administratively edited by Amendment 1?
The amendment makes administrative edits across multiple sections, including 1.1, 1.2, 2.1.2, 3.1, 3.2, and 5.2.6.
14) What changed in Section 2.1.1 under Amendment 1?
Amendment 1 replaces Section 2.1.1 with new language dealing specifically with FFRDCs and government entities.
15) Did Amendment 1 change the evaluation criteria?
Yes. Amendment 1 updates the evaluation criteria by revising Evaluation Criteria #2 in Section 4.2 to remove a reference to government entities. The amendment notes that this particular removal is not highlighted.
16) Were changes in Amendment 1 highlighted in the document?
The amendment notes that changes are highlighted in yellow, except for the one evaluation-criteria edit (the removal of a reference to government entities in Evaluation Criteria #2), which is noted as not highlighted.
17) What terminology change did Amendment 1 make regarding proposal content?
Amendment 1 changes terminology throughout the document from "Abstract" to "Solution Summaries" without changing the underlying intent.
18) Did Amendment 1 update proposal submission instructions?
Yes. Amendment 1 updates proposal submission instructions in Section 3.2.
19) What happened to the Stage 2 Notification Letter?
Amendment 1 removes the Stage 2 Notification Letter from Section 5.1.
20) Why was the title revised in the listing?
The listing clarifies a naming issue: the title was revised to reduce confusion because it should have been labeled "Master Announcement Instruction (MAI)" rather than "ARPA-H BDF Tool Box."
21) What instrument type is shown for this opportunity listing?
Administrative details in the listing describe the instrument type as a cooperative agreement under a discretionary program.
22) What activity categories are associated with the listing?
The activity categories span health and science and technology research and development.
23) What is the CFDA/Assistance Listing number shown?
The CFDA/Assistance Listing number shown in the listing is 93.384.
24) The listing shows a closing date. Does that mean I should submit to the MAI by that date?
The listing includes an original closing date of October 20, 2024, but the key practical point remains: applicants should not submit proposals to the MAI itself. Proposals are submitted only in response to a specific Module Announcement that incorporates the MAI.
25) What should applicants do to understand the exact requirements for a specific opportunity?
Applicants should review the specific Module Announcement, because it is expected to explain how tiers apply for that opportunity and what materials are required at each tier, along with the module-specific scope and requirements.
26) What is the main practical takeaway for applicants?
The MAI is a standard instruction set, not a standalone solicitation. Applicants should watch for and respond to ARPA-H Module Announcements that reference the MAI, and follow the module-specific requirements and tier structure described there.
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