Opportunity Information: Apply for G23AS00435

The U.S. Geological Survey (USGS) is soliciting proposals for a discretionary cooperative agreement through the North Atlantic Coast Cooperative Ecosystem Studies Unit (CESU). The project focus is tick-borne disease ecology, specifically how tick-borne pathogens interact with the broader tick microbiome and how environmental conditions and host communities shape those interactions. The overall goal is to improve scientific understanding of the biological and ecological drivers that influence pathogen presence and prevalence in ticks, with an emphasis on integrating molecular "omics" approaches with field-based comparisons.

A central technical component of the work is the use of shotgun metatranscriptomics, along with other omics methods as appropriate, to characterize active biological signals within ticks and to evaluate interactions among all members of the tick-associated microbial community. This is explicitly multi-domain, meaning the work should consider prokaryotes (bacteria and archaea), eukaryotes (such as protozoa or fungi where relevant), and viruses, rather than focusing on a single group. By looking at the broader microbiota and its activity, the study aims to clarify how microbial community composition and function may facilitate, inhibit, or otherwise influence tick-borne pathogens.

The second major component is field-based comparative research designed to test how environmental factors and potential host animals affect both microbiome composition and tick-borne pathogen prevalence. In practice, this implies sampling ticks across contrasting environmental settings and host contexts, then linking ecological variables (for example habitat type, climate-related conditions, seasonality, land use, or host availability) to measured differences in microbial communities and pathogen detection. The opportunity is framed around understanding these relationships in real-world conditions, not only in laboratory settings, so applicants would be expected to build a study design that supports comparisons across sites, conditions, or host assemblages.

This funding opportunity is issued under the CESU Program, which is a network of partnerships intended to support collaborative research, technical assistance, and education connected to natural and cultural resource science. Because it is a CESU award, eligibility is limited: applicants must be a participating partner within the North Atlantic Coast CESU. The award mechanism is a cooperative agreement, which typically indicates substantial involvement by the federal agency in the project (such as collaboration on study design, coordination, data sharing, or other scientific involvement) rather than a more hands-off grant relationship.

Key administrative details include the funding opportunity number G23AS00435, issued by the USGS (Department of the Interior) under CFDA 15.808, with an activity category of Science and Technology and other Research and Development. The award ceiling is $199,880. The opportunity was created on 2023-06-28 and had an original closing date of 2023-07-28. Expected awards are not specified in the provided source text.

  • The Geological Survey in the science and technology and other research and development sector is offering a public funding opportunity titled "Cooperative Agreement for CESU-affiliated Partner with North Atlantic Coast Cooperative Ecosystem Studies Unit" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 15.808.
  • This funding opportunity was created on 2023-06-28.
  • Applicants must submit their applications by 2023-07-28. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $199,880.00 in funding.
  • Eligible applicants include: Others.
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