Opportunity Information: Apply for DE FOA 0002448
This funding opportunity (DE-FOA-0002448) is a discretionary research grant announcement from the U.S. Department of Energy (DOE), Office of Science, within the Biological and Environmental Research (BER) program. It sits specifically in the Biological Systems Science Division (BSSD) Genomic Science Program (GSP) mission space, meaning the emphasis is on genome-enabled, systems-level biology that can be translated into capabilities important to DOE energy and environmental goals. The overall aim is to expand the scientific foundation needed to use microbes more effectively for producing next-generation biofuels and bioproducts, and to push forward biology-based solutions for breaking down certain synthetic polymers into reusable chemical building blocks.
The FOA is centered on two main research directions. The first track focuses on systems biology research that advances the development of promising new model organisms and microbial functional capabilities. In practice, this means identifying, characterizing, and improving microbes (including non-traditional or emerging organisms) that have traits useful for bioenergy applications, and building the kind of foundational knowledge that turns them into reliable experimental and engineering platforms. It also includes discovering and understanding biosynthetic pathways that microbes use (or could be engineered to use) to produce fuels and other valuable bioproducts. The underlying idea is that if researchers can map and predict how these organisms function at the genetic, regulatory, and metabolic levels, they can more rationally design microbial systems that perform well under real process conditions and produce targeted molecules efficiently.
The second track targets research into metabolic pathways capable of synthetic polymer deconstruction and conversion to recycled monomers. This is aimed at understanding and enabling biological or bio-inspired routes for breaking down man-made polymer materials and transforming them into monomers that can be reused, supporting a more circular approach to materials and carbon. Rather than simply studying degradation as an environmental fate process, the emphasis here is on the mechanistic biology and metabolism that would allow controlled deconstruction and productive conversion, which aligns with broader goals around sustainable manufacturing and waste reduction.
From an administrative standpoint, the award instrument is a grant, and the funding activity category is science and technology research and development. The opportunity lists an award ceiling of $500,000, with an expectation of around 15 awards, indicating a competitive program intended to support a portfolio of projects rather than a single large center. The CFDA number is 81.049. The announcement was created on December 3, 2020, with an original application deadline of April 6, 2021. Eligibility is listed as "Others" with additional eligibility details referenced in the full announcement, which typically signals that eligibility may include a range of institution types depending on the FOA language (for example, universities, national laboratories, nonprofits, or other research entities), but applicants would need to confirm the exact allowable applicant categories in the complete text.
In short, this DOE Office of Science FOA is designed to fund genomics- and systems biology-driven research that strengthens the microbial science toolkit for biofuel and bioproduct manufacturing, while also advancing biological understanding and capability for breaking down certain synthetic polymers into recyclable monomers. The common thread across both areas is building predictive, mechanistic knowledge of microbial pathways and functions so they can be harnessed and improved for energy-relevant, sustainability-focused outcomes.Apply for DE FOA 0002448
- The Department of Energy - Office of Science, Office of Science in the science and technology and other research and development sector is offering a public funding opportunity titled "SYSTEMS BIOLOGY OF BIOENERGY-RELEVANT MICROBES TO ENABLE PRODUCTION OF NEXT-GENERATION BIOFUELS AND BIOPRODUCTS" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 81.049.
- This funding opportunity was created on Dec 03, 2020.
- Applicants must submit their applications by Apr 06, 2021. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- The number of recipients for this funding is limited to 15 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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