Opportunity Information: Apply for PAR 23 132
The National Institute of Dental and Craniofacial Research (NIDCR), part of the National Institutes of Health (NIH), is offering a Small Research Grant (R03) opportunity focused on studies that use existing and publicly available genomics data to answer research questions relevant to human dental, oral, and craniofacial (DOC) diseases and conditions. The central idea is to fund smaller, targeted projects that apply data science and analytic methods to already-collected genomics datasets, rather than generating new genomics data. This funding opportunity is explicitly labeled "Clinical Trial Not Allowed," meaning applicants must propose projects that do not involve conducting clinical trials; the work should instead be based on secondary analysis of existing data resources.
The opportunity is identified as PAR 23 132 and falls under a discretionary grant mechanism in the health category, with CFDA number 93.121. As an R03, it is designed for concise, well-scoped research aims that can be completed with limited resources and within a shorter timeframe than larger NIH research project grants. The emphasis on analyzing existing datasets suggests NIDCR is looking for projects that can move quickly and efficiently, extracting new biological or clinical insights about DOC conditions by leveraging modern computational approaches such as statistical genetics, bioinformatics, machine learning, or other rigorous data science techniques appropriate for genomics.
Eligibility is broad and includes many types of domestic U.S. applicants, such as state, county, city, and township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; and federally recognized Native American tribal governments. It also allows applications from public housing authorities/Indian housing authorities, Native American tribal organizations that are not federally recognized tribal governments, and both nonprofit organizations (with or without 501(c)(3) status) as well as for-profit organizations (including small businesses and for-profits other than small businesses). In addition, the announcement highlights a wide range of "other eligible applicants," including Alaska Native and Native Hawaiian Serving Institutions; Asian American, Native American, and Pacific Islander Serving Institutions (AANAPISIs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); faith-based or community-based organizations; eligible federal agencies; regional organizations; U.S. territories or possessions; and even non-domestic (non-U.S.) entities (foreign organizations). In practice, this means the program is open to many research-performing organizations, including those serving historically underrepresented communities and organizations outside the United States, as long as they can carry out the proposed analyses and meet NIH requirements.
The posted original closing date is 2026-05-07. The source information does not specify an award ceiling or the expected number of awards, so applicants would typically need to consult the full FOA text and NIH grants policy details for budget limits and other administrative parameters commonly associated with the R03 mechanism. Overall, this opportunity is best suited for investigators who can define a clear, high-impact question in dental, oral, or craniofacial health and answer it by reanalyzing existing genomics data using robust computational and statistical methods, without collecting new clinical trial data.Apply for PAR 23 132
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIDCR Small Research Grants for Analyses of Existing Genomics Data (R03 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121.
- This funding opportunity was created on 2023-03-28.
- Applicants must submit their applications by 2026-05-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is this funding opportunity?
This is a National Institute of Dental and Craniofacial Research (NIDCR), NIH Small Research Grant (R03) opportunity (PAR 23 132) supporting research that uses existing, publicly available genomics datasets to answer questions relevant to human dental, oral, and craniofacial (DOC) diseases and conditions.
Who is offering the grant?
The opportunity is offered by the National Institute of Dental and Craniofacial Research (NIDCR), which is part of the National Institutes of Health (NIH).
What grant mechanism is being used?
The mechanism is an NIH R03 (Small Research Grant). R03 awards are intended for smaller, targeted projects with concise, well-scoped aims that can be completed with limited resources and within a shorter timeframe than larger NIH research project grants.
What is the main scientific focus of the program?
The focus is on dental, oral, and craniofacial (DOC) diseases and conditions in humans, specifically through studies that analyze existing genomics data to generate new biological or clinically meaningful insights.
Does this opportunity support generating new genomics data?
The emphasis is on secondary analysis of already-collected genomics datasets that are existing and publicly available, rather than generating new genomics data.
What types of data are applicants expected to use?
Applicants are expected to use existing and publicly available genomics datasets. The opportunity is centered on leveraging these resources to answer DOC-relevant research questions through computational and statistical analysis.
What kinds of methods or approaches are encouraged?
The description highlights data science and analytic approaches appropriate for genomics, including statistical genetics, bioinformatics, machine learning, and other rigorous computational and statistical methods.
Are clinical trials allowed under this funding opportunity?
No. The opportunity is explicitly labeled "Clinical Trial Not Allowed." Proposed projects must not involve conducting clinical trials and should instead rely on secondary analysis of existing data resources.
If clinical trials are not allowed, what kind of work is appropriate?
Work that fits this program includes reanalysis of existing and publicly available genomics data to address DOC-related research questions using robust analytics, without enrolling participants into a trial or conducting trial-related interventions.
What is the opportunity number or identifier?
The opportunity is identified as PAR 23 132.
What is the CFDA number for this opportunity?
The CFDA number listed is 93.121.
What category and mechanism type is this opportunity listed under?
It is listed as a discretionary grant mechanism in the health category.
Who is eligible to apply?
Eligibility is broad and includes many types of applicants, including domestic U.S. entities and non-U.S. (foreign) organizations, as well as organizations serving historically underrepresented communities, provided they can carry out the proposed analyses and meet NIH requirements.
Are U.S. government entities eligible?
Yes. Eligible applicants include state, county, city, and township governments, as well as special district governments.
Are educational institutions eligible?
Yes. Eligible applicants include independent school districts, public and state-controlled institutions of higher education, and private institutions of higher education.
Are tribal governments and tribal organizations eligible?
Yes. Federally recognized Native American tribal governments are eligible. Native American tribal organizations that are not federally recognized tribal governments are also listed as eligible.
Are nonprofits eligible to apply?
Yes. Nonprofit organizations are eligible, including those with 501(c)(3) status and those without 501(c)(3) status.
Are for-profit organizations eligible?
Yes. For-profit organizations are eligible, including small businesses and for-profits other than small businesses.
Are public housing authorities eligible?
Yes. Public housing authorities/Indian housing authorities are listed as eligible applicants.
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are included among the "other eligible applicants" highlighted in the description.
Are minority-serving institutions specifically mentioned as eligible?
Yes. The opportunity highlights eligibility for Alaska Native and Native Hawaiian Serving Institutions; Asian American, Native American, and Pacific Islander Serving Institutions (AANAPISIs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); and Tribally Controlled Colleges and Universities (TCCUs).
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are listed among other eligible applicants.
Are non-U.S. (foreign) organizations eligible to apply?
Yes. The description explicitly includes non-domestic (non-U.S.) entities (foreign organizations) among eligible applicants.
Are federal agencies eligible to apply?
Yes. The description includes eligible federal agencies among other eligible applicants.
Is there a specific deadline mentioned?
Yes. The posted original closing date is 2026-05-07.
Is an award ceiling or the expected number of awards provided in the summary?
No. The provided information does not specify an award ceiling or the expected number of awards.
Where would an applicant typically find budget limits and other administrative details?
Based on the summary, applicants would typically consult the full Funding Opportunity Announcement (FOA) text and NIH grants policy details for budget limits and other administrative parameters commonly associated with the R03 mechanism.
What kind of project scope is this opportunity best suited for?
It is best suited for a clear, targeted project with well-defined aims that can efficiently produce new insights about human DOC diseases and conditions by reanalyzing existing genomics data using rigorous computational approaches.
What is the central idea behind funding these projects?
The central idea is to support smaller, targeted studies that can move quickly by applying data science and analytics to already-collected genomics datasets, rather than spending time and resources generating new genomics data.
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