Opportunity Information: Apply for RFA HD 17 009

The Autism Centers of Excellence: Centers (P50) opportunity (RFA-HD-17-009) is a discretionary grant program run through the National Institutes of Health, led by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) with participation from other NIH Institutes. It is designed to support large, center-style autism research programs that bring multiple disciplines together under one coordinated structure. The central idea is integration: applicants are expected to propose a set of linked research projects and shared core resources that clearly reinforce one another, creating cohesion and synergy rather than a collection of unrelated studies.

This funding uses the NIH P50 Specialized Center mechanism, which typically supports multi-project centers with a unifying scientific theme, several interdependent projects, and cores that provide shared services, infrastructure, data resources, or specialized methods across the center. In practical terms, an ACE Center application would be expected to show how each research project benefits from the center environment and how the cores help the projects operate more efficiently, generate higher-quality data, and produce outcomes that would be difficult to achieve through separate standalone awards. The program emphasis is on coordinated, multidisciplinary autism research, fitting within NIH priorities spanning health and human development.

The announcement also points applicants to a companion funding opportunity for Autism Centers of Excellence Networks supported through the R01 mechanism (RFA-HD-17-008). While the P50 center mechanism focuses on an integrated center with multiple projects and cores housed within an organized program, the companion R01 network opportunity is meant for networked research structures supported by individual R01 awards. Together, these FOAs reflect a broader NIH strategy to fund both center-based integration and cross-site network collaboration in autism research, depending on the structure and goals of the proposed work.

Eligibility is broad and includes many types of U.S.-based organizations and government entities. Eligible applicants include state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities and Indian housing authorities; Native American tribal organizations that are not federally recognized governments; nonprofits with and without 501(c)(3) status (excluding institutions of higher education where applicable); for-profit organizations other than small businesses; and small businesses. The FOA explicitly highlights additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions. This reflects an intent to encourage participation from a wide range of institutions, including those serving historically underrepresented communities.

At the same time, the opportunity draws a clear line around non-U.S. applicants. Non-domestic (non-U.S.) entities (foreign organizations and foreign institutions) are not eligible to apply, and non-domestic components of U.S. organizations are also not eligible to apply. However, the FOA allows foreign components as defined by the NIH Grants Policy Statement, meaning a U.S. applicant organization can include certain foreign elements in the proposed work when they meet NIH policy definitions and requirements. In other words, the applicant organization must be U.S.-based and eligible, but specific parts of the project may involve foreign activities under NIH rules.

From the funding details provided, the program is categorized under environment, health, income security, and social services and is associated with CFDA numbers 93.113, 93.173, 93.242, 93.853, and 93.865. The listed award ceiling is $1,500,000, indicating an upper limit on yearly direct costs or total costs depending on the FOA specifics (the exact interpretation would normally be clarified in the full NIH announcement). The original closing date was 2016-11-17, and the FOA creation date was 2016-07-12, placing this as a time-limited solicitation from that cycle. Overall, the grant is aimed at supporting substantial, coordinated autism research centers that can leverage shared infrastructure and team science to accelerate progress beyond what single-project awards can typically achieve.

  • The National Institutes of Health in the environment, health, income security and social services sector is offering a public funding opportunity titled "Autism Centers of Excellence: Centers (P50)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.173, 93.242, 93.853, 93.865.
  • This funding opportunity was created on 2016-07-12.
  • Applicants must submit their applications by 2016-11-17. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $1,500,000.00 in funding.
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Fertility Status as a Marker for Overall Health (R21 Clinical Trial Optional) Apply for PA 18 049

Funding Number: PA 18 049
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Research on Autism Spectrum (R21- Clinical Trial Optional) Apply for PA 18 400

Funding Number: PA 18 400
Agency: National Institutes of Health
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Research on Autism Spectrum (R03-Clinical Trial Optional) Apply for PA 18 399

Funding Number: PA 18 399
Agency: National Institutes of Health
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Research on Autism Spectrum (R01- Clinical Trial Optional) Apply for PA 18 401

Funding Number: PA 18 401
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Global Brain and Nervous System Disorders Research Across the Lifespan (R01 Clinical Trials Optional) Apply for PAR 18 835

Funding Number: PAR 18 835
Agency: National Institutes of Health
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Global Brain and Nervous System Disorders Research Across the Lifespan (R21 Clinical Trial Optional) Apply for PAR 18 836

Funding Number: PAR 18 836
Agency: National Institutes of Health
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Funding Number: RFA MH 19 121
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U.S.-Brazil Collaborative Biomedical Research Program (R01 Clinical Trial Optional) Apply for RFA AI 18 054

Funding Number: RFA AI 18 054
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Mechanistic Studies of Gene-Environment Interplay in Dental, Oral, Craniofacial, and Other Diseases and Conditions (R01 Clinical Trial Not Allowed) Apply for PAR 19 292

Funding Number: PAR 19 292
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Development of Novel and Robust Systems for Mechanistic Studies of Gene-Environment Interplay in Dental, Oral, Craniofacial, and Other Diseases and Conditions (R21 Clinical Trial Not Allowed) Apply for PAR 19 293

Funding Number: PAR 19 293
Agency: National Institutes of Health
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Small Research Grants for Establishing Basic Science-Clinical Collaborations to Understand Structural Birth Defects (R03 Clinical Trial Not Allowed) Apply for PAR 20 065

Funding Number: PAR 20 065
Agency: National Institutes of Health
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Small Research Grants for Analyses of Down Syndrome-related Research Data for the INCLUDE Project (R03 Clinical Trial Not Allowed) Apply for RFA OD 20 006

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Funding Number: RFA OD 20 005
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Research on Autism Spectrum Disorders (R01 Clinical Trial Optional) Apply for PA 21 201

Funding Number: PA 21 201
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Research on Autism Spectrum Disorders (R21 Clinical Trial Optional) Apply for PA 21 200

Funding Number: PA 21 200
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Research on Autism Spectrum Disorders (R03 Clinical Trial Optional) Apply for PA 21 199

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