Opportunity Information: Apply for RFA CA 23 016
The National Institutes of Health, through the National Cancer Institute (NCI), is soliciting applications for a Cooperative Agreement (U24) under the Informatics Technology for Cancer Research (ITCR) Program to support the advanced development of emerging informatics technologies for cancer research and management. This opportunity, titled "Advanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)" (RFA-CA-23-016), is aimed at projects that will strengthen how cancer-related data and knowledge are acquired, managed, analyzed, and shared across the full cancer research continuum. That continuum explicitly includes areas such as cancer biology, diagnosis and treatment, early detection, risk assessment and prevention, cancer control and epidemiology, and cancer health disparities.
A key point is that this funding is not meant for brand-new prototypes or very early proof-of-concept ideas. Instead, it targets "emerging" informatics technologies that have already moved beyond initial prototyping and pilot development, have shown strong promise for broader impact, and now need additional enhancement to become more robust, scalable, and useful to the wider cancer research community. At the same time, the technology should not already be widely adopted in the field; the intent is to help promising tools cross the gap between a successful pilot and real-world, community-level uptake.
Because this is a U24 cooperative agreement, applicants should expect substantial involvement from NCI staff compared with a typical research grant. In practice, that usually means the project will be carried out in collaboration with the NIH program team, with shared expectations around milestones, progress monitoring, and alignment with ITCR priorities. The FOA emphasizes that successful applications must clearly justify why the technology is needed now, what specific gap or priority need it addresses in cancer research, and how its further development will produce tangible benefits for the community. Another major expectation is ongoing engagement with end users and collaborators: applicants are expected to build in mechanisms to actively solicit, incorporate, and respond to feedback throughout the development process, rather than treating usability and adoption as afterthoughts.
The announcement also clarifies where this FOA sits within the broader ITCR ecosystem. If a team is looking for support for early-stage development (for example, building the first functional prototype) or for long-term sustainment of an existing informatics resource, they are directed to consult the companion funding opportunities rather than this one. In other words, this FOA is specifically about advancing and enhancing a tool that is already working at a basic level, but needs significant development to reach broader readiness and impact.
Eligibility is broad and includes many types of organizations: state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; other Native American tribal organizations; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status; for-profit organizations other than small businesses; and small businesses. The FOA also explicitly highlights additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, AANAPISI institutions, Hispanic-serving institutions, Historically Black Colleges and Universities, Tribally Controlled Colleges and Universities, faith-based or community-based organizations, eligible federal agencies, regional organizations, U.S. territories or possessions, and non-U.S. (foreign) entities.
From an administrative standpoint, the opportunity is categorized as discretionary funding and aligns with NIH health and education-related activity categories. The CFDA/assistance listing numbers associated with the opportunity are 93.393, 93.394, 93.395, 93.396, and 93.399. The source information provided lists an award ceiling of $600,000, a creation date of 2022-12-22, and an original closing date of 2023-11-17. The FOA is also labeled "Clinical Trial Optional," meaning applicants may propose projects that include a clinical trial if appropriate, but a clinical trial is not required for all applications.
Overall, this grant opportunity is designed to help move promising cancer informatics technologies from successful early demonstrations into more mature, enhanced, and broadly usable products or platforms. The strongest proposals will pair a compelling cancer research need with a realistic, user-informed development plan that shows how the technology will become more impactful, more usable, and more adoptable by the broader cancer research community.Apply for RFA CA 23 016
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Advanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393, 93.394, 93.395, 93.396, 93.399.
- This funding opportunity was created on 2022-12-22.
- Applicants must submit their applications by 2023-11-17. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $600,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Applicants who have applied for this opportunity (RFA CA 23 016) also looked into and applied for these:
| Funding Opportunity |
|---|
| Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional) Apply for RFA CA 23 015 Funding Number: RFA CA 23 015 Agency: National Institutes of Health Category: Education, Health Funding Amount: $300,000 |
| Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional) Apply for RFA CA 23 017 Funding Number: RFA CA 23 017 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Translational Centers for Microphysiological Systems (TraCe MPS) (U2C Clinical Trials Not Allowed) Apply for RFA TR 23 001 Funding Number: RFA TR 23 001 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NIDA Core "Center of Excellence" Grant Program (P30 Clinical Trial Optional) Apply for PAR 23 049 Funding Number: PAR 23 049 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Revision Applications for Validation of Biomarker Assays Developed Through NIH-Supported Research Grants (R01 Clinical Trial Not Allowed) Apply for PAR 23 088 Funding Number: PAR 23 088 Agency: National Institutes of Health Category: Education, Health Funding Amount: $150,000 |
| NIDA Program Project Grant Applications (P01 Clinical Trial Optional) Apply for PAR 23 064 Funding Number: PAR 23 064 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NIDA Research Center of Excellence Grant Program (P50 Clinical Trial Optional) Apply for PAR 23 076 Funding Number: PAR 23 076 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Career Enhancement Award to Advance Research on Firearm Injury and Mortality Prevention (K18 Independent Clinical Trial Required) Apply for PAR 23 107 Funding Number: PAR 23 107 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Career Enhancement Award to Advance Research on Firearm Injury and Mortality Prevention (K18 Independent Clinical Trial Not Allowed) Apply for PAR 23 108 Funding Number: PAR 23 108 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Accelerating the Pace of Drug Abuse Research Using Existing Data (R21 Clinical Trial Optional) Apply for RFA DA 24 037 Funding Number: RFA DA 24 037 Agency: National Institutes of Health Category: Education, Health Funding Amount: $275,000 |
| Education Activities for Responsible Analyses of Complex, Large-Scale Data (R25- Clinical Trial Not Allowed) Apply for RFA DA 24 027 Funding Number: RFA DA 24 027 Agency: National Institutes of Health Category: Education, Health Funding Amount: $300,000 |
| Leveraging Big Data Science to Elucidate the Mechanisms of HIV Activity and Interaction with Substance Use Disorder (R21 Clinical Trials Not Allowed) Apply for RFA DA 24 009 Funding Number: RFA DA 24 009 Agency: National Institutes of Health Category: Education, Health Funding Amount: $275,000 |
| Leveraging Big Data Science to Elucidate the Mechanisms of HIV Activity and Interaction with Substance Use Disorder (R01 Clinical Trials Not Allowed) Apply for RFA DA 24 008 Funding Number: RFA DA 24 008 Agency: National Institutes of Health Category: Education, Health Funding Amount: $350,000 |
| Advancing Integrated Models (AIM) of Care to Improve Pregnancy Outcomes among Women Who Experience Persistent Disparities (R01 Clinical Trial Optional) Apply for RFA NR 23 002 Funding Number: RFA NR 23 002 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Evaluating the Impact of Pandemic Era related Food and Housing Policies and Programs on Health Outcomes in Health Disparity Populations (R01 Clinical Trial Optional) Apply for RFA NR 23 003 Funding Number: RFA NR 23 003 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Clinical-Community Linkages to Address Social Needs and Social Conditions to Advance Health Equity among Populations Experiencing Health Disparities: The Bridge-to-Care Initiative (R01 Clinical Trial Required) Apply for RFA NR 23 004 Funding Number: RFA NR 23 004 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Ex Vivo Models for Studies at the Intersection of HIV and Poly-Substance Use (R01 Clinical Trial Not Allowed) Apply for RFA DA 24 001 Funding Number: RFA DA 24 001 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Genomic Community Resources (U24 Clinical Trial Not Allowed) Apply for PAR 23 124 Funding Number: PAR 23 124 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Addressing the Primary Care Needs of Cancer Survivors (U01 Clinical Trial Required) Apply for RFA CA 23 025 Funding Number: RFA CA 23 025 Agency: National Institutes of Health Category: Education, Health Funding Amount: $750,000 |
| Avenir Award Program for Research on Substance Use Disorders and HIV (DP2 Clinical Trial Optional) Apply for PAR 23 125 Funding Number: PAR 23 125 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
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